MethodsSearch strategy and selection criteriaWe conducted a systematic review of cohort studies that reported associations between AF and death or cardiovascular events in men and women. This was done in accordance with the MOOSE (meta analysis of observational studies in epidemiology) guidelines.15 An experienced research librarian designed and conducted the search strategy. Medline and Embase were searched from 1966 to March 2015 with a combined text and MeSH subheading search with the following terms: “atrial fibrillation”, “mortality”, “death”, “cardiovascular disease”, “heart failure”, “myocardial infarction”, “death, sudden, cardiac”, “stroke”, “kidney”, “renal”, “peripheral”, and “risk factors”.
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